CpG-ODN免疫佐剂
CPG ODN(CpG oligonucleotide, CpG寡脱氧核苷酸)是人工合成的含有非甲基化的胞嘧啶鸟嘌呤二核苷酸(CpG)的寡脱氧核苷酸(ODN),可模拟细菌DNA刺激多种哺乳动物包括人的免疫细胞。不同类型的CpG ODN的结构特征与免疫效应各有不同,一般分为A、B、C三类,泓迅生物能够提供多种属的三种类型的CpG ODN。
● A类CpG ODN以含有CpG二核苷酸的回文序列为核心,两端为poly G尾,磷酸二酯键骨架为部分硫代修饰,通过回文序列和poly G形成高级结构,能够活化浆细胞样树突状细胞诱生大量I型干扰素,对B细胞活性弱。
● B类CpG ODN是一种全硫代修饰的线性CpG ODN,对B细胞有很强的免疫刺激活性,但不能活化浆细胞样树突状细胞。
● C类CpG-ODN是一类全硫代修饰的CpG ODN,能通过回文序列形成二聚体,兼具A型和B型CpG-ODN的活性,既能活化浆细胞样树突状细胞,又能活化B细胞。
产品优势
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- 纯度>95%
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- 内毒素水平<5EU/mg
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- 稳定性极佳
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- 批次一致性
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产品列表
Name
|
Cat(#)
|
Species
|
Size/Tube
|
CpG ODN 1585
|
SOC-A1585
|
Mouse
|
1mg
|
CpG ODN 2216
|
SOC-A2216
|
Human Preferred
|
1mg
|
CpG ODN 2336
|
SOC-A2336
|
Human Preferred
|
1mg
|
CpG ODN 1668
|
SOC-B1668
|
Mouse
|
1mg
|
CpG ODN 1826
|
SOC-B1826
|
Mouse
|
1mg
|
CpG ODN 2006/7909
|
SOC-B2006
|
Human Preferred
|
1mg
|
CpG ODN 2007
|
SOC-B2007
|
Bovine/Porcine
|
1mg
|
CpG ODN BW006/684
|
SOC-BW006
|
Human&Mouse
|
1mg
|
CpG ODN D-SL01
|
SOC-BDSL01
|
Multispecies
|
1mg
|
CpG ODN 2395
|
SOC-C2395
|
Human/Mouse
|
1mg
|
CpG ODN M362
|
SOC-CM362
|
Human/Mouse
|
1mg
|
CpG ODN D-SL03
|
SOC-CDSL03
|
Multispecies
|
1mg
|
CpG ODN 10101
|
SOC-10101
|
Human&Mouse
|
1mg
|
CpG ODN IMT504
|
SOC-IMT504
|
Human&Mouse
|
1mg
|
CpG ODN 1982
|
SOC-1982
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Human&Mouse
|
1mg
|
CpG ODN 2088
|
SOC-2088
|
Human&Mouse
|
1mg
|
CpG ODN 21158
|
SOC-21158
|
Human&Mouse
|
1mg
|
CpG ODN 4084-F
|
SOC-4084-F
|
Human&Mouse
|
1mg
|
CpG ODN 5328
|
SOC-5328
|
Human&Mouse
|
1mg
|
CpG ODN BW001
|
SOC-BW001
|
Human&Mouse
|
1mg
|
CpG ODN INH-1
|
SOC-INH-1
|
Human&Mouse
|
1mg
|
CpG ODN M326
|
SOC-M326
|
Human&Mouse
|
1mg
|
CpG ODN TTAGGG
|
SOC-TTAGGG
|
Human&Mouse
|
1mg
|
常见问题
发货形式默认1 mg/管发货,不分装。客户收到后可以溶解分装冷冻,一次取用一管。
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